16 October 2021
Round 1
Bryncoch		v	Mumbles Rngrs Albion
Camford		v	Peniel
CK Swiss Valley		v	Cwrt Herbert Colts
Clydach		v	Merlins Bridge
Coedffranc		v	Glynneath
Cwm Wanderers		v	Clarbeston Road
Garden Village		v	Treboeth United
Llangennech		v	Giants Grave BGC
Llangyfelach		v	Bonymaen
Milford United		v	Ystradgynlais
Mumbles Rangers		v	Dunvant & 3 Crosses
Penlan Colts		v	St Clears
Sandfields		v	Ynystawe Athletic
Saron		v	Ynystawe Colts
Seaside		v	Carmarthen Stars
St Josephs Colts Whites		v	Loughor Rovers
Talycopa		v	Pontarddulais Town
Tenby		v	Bryncoch Yellows
Ynysygerwn		v	Neyland