24 October 2021
Preliminary Round
Amman United		v	Pontyberem
Carmarthen Quins		v	Carmarthen Athletic
Lampeter		v	Llandeilo
Llangennech		v	Felinfoel
Newcastle Emlyn		v	Bye
Penybanc		v	Bye
St Clears		v	Bye
Tumble		v	Burry Port