3 September 2022
Aberystwyth		v	Penclawdd
Felinfoel		v	Whitland
Gorseinon		v	Llanelli Wanderers
Gowerton		v	Yr Hendy
Newcastle Emlyn		v	Crymych
Pembroke		v	Llangennech

10 September 2022
Crymych		v	Aberystwyth
Llanelli Wanderers		v	Felinfoel
Llangennech		v	Newcastle Emlyn
Penclawdd		v	Gorseinon
Whitland		v	Gowerton
Yr Hendy		v	Pembroke

24 September 2022
Aberystwyth		v	Newcastle Emlyn
Felinfoel		v	Penclawdd
Gorseinon		v	Crymych
Gowerton		v	Llanelli Wanderers
Llangennech		v	Yr Hendy
Pembroke		v	Whitland

1 October 2022
Aberystwyth		v	Gorseinon
Crymych		v	Felinfoel
Llanelli Wanderers		v	Pembroke
Newcastle Emlyn		v	Yr Hendy
Penclawdd		v	Gowerton
Whitland		v	Llangennech

8 October 2022
Felinfoel		v	Aberystwyth
Gorseinon		v	Newcastle Emlyn
Gowerton		v	Crymych
Llangennech		v	Llanelli Wanderers
Pembroke		v	Penclawdd
Yr Hendy		v	Whitland

22 October 2022
Aberystwyth		v	Gowerton
Crymych		v	Pembroke
Gorseinon		v	Felinfoel
Llanelli Wanderers		v	Yr Hendy
Newcastle Emlyn		v	Whitland
Penclawdd		v	Llangennech

12 November 2022
Felinfoel		v	Newcastle Emlyn
Gowerton		v	Gorseinon
Llangennech		v	Crymych
Pembroke		v	Aberystwyth
Whitland		v	Llanelli Wanderers
Yr Hendy		v	Penclawdd

3 December 2022
Aberystwyth		v	Llangennech
Crymych		v	Yr Hendy
Felinfoel		v	Gowerton
Gorseinon		v	Pembroke
Newcastle Emlyn		v	Llanelli Wanderers
Penclawdd		v	Whitland

10 December 2022
Gowerton		v	Newcastle Emlyn
Llanelli Wanderers		v	Penclawdd
Llangennech		v	Gorseinon
Pembroke		v	Felinfoel
Whitland		v	Crymych
Yr Hendy		v	Aberystwyth

17 December 2022
Aberystwyth		v	Whitland
Crymych		v	Llanelli Wanderers
Felinfoel		v	Llangennech
Gorseinon		v	Yr Hendy
Gowerton		v	Pembroke
Newcastle Emlyn		v	Penclawdd

7 January 2023
Llanelli Wanderers		v	Aberystwyth
Llangennech		v	Gowerton
Pembroke		v	Newcastle Emlyn
Penclawdd		v	Crymych
Whitland		v	Gorseinon
Yr Hendy		v	Felinfoel

14 January 2023
Crymych		v	Newcastle Emlyn
Llanelli Wanderers		v	Gorseinon
Llangennech		v	Pembroke
Penclawdd		v	Aberystwyth
Whitland		v	Felinfoel
Yr Hendy		v	Gowerton

21 January 2023
Aberystwyth		v	Crymych
Felinfoel		v	Llanelli Wanderers
Gorseinon		v	Penclawdd
Gowerton		v	Whitland
Newcastle Emlyn		v	Llangennech
Pembroke		v	Yr Hendy

28 January 2023
Crymych		v	Gorseinon
Llanelli Wanderers		v	Gowerton
Newcastle Emlyn		v	Aberystwyth
Penclawdd		v	Felinfoel
Whitland		v	Pembroke
Yr Hendy		v	Llangennech

18 February 2023
Felinfoel		v	Crymych
Gorseinon		v	Aberystwyth
Gowerton		v	Penclawdd
Llangennech		v	Whitland
Pembroke		v	Llanelli Wanderers
Yr Hendy		v	Newcastle Emlyn

4 March 2023
Aberystwyth		v	Felinfoel
Crymych		v	Gowerton
Llanelli Wanderers		v	Llangennech
Newcastle Emlyn		v	Gorseinon
Penclawdd		v	Pembroke
Whitland		v	Yr Hendy

25 March 2023
Felinfoel		v	Gorseinon
Gowerton		v	Aberystwyth
Llangennech		v	Penclawdd
Pembroke		v	Crymych
Whitland		v	Newcastle Emlyn
Yr Hendy		v	Llanelli Wanderers

1 April 2023
Aberystwyth		v	Pembroke
Crymych		v	Llangennech
Gorseinon		v	Gowerton
Llanelli Wanderers		v	Whitland
Newcastle Emlyn		v	Felinfoel
Penclawdd		v	Yr Hendy

8 April 2023
Gowerton		v	Felinfoel
Llanelli Wanderers		v	Newcastle Emlyn
Llangennech		v	Aberystwyth
Pembroke		v	Gorseinon
Whitland		v	Penclawdd
Yr Hendy		v	Crymych

15 April 2023
Aberystwyth		v	Yr Hendy
Crymych		v	Whitland
Felinfoel		v	Pembroke
Gorseinon		v	Llangennech
Newcastle Emlyn		v	Gowerton
Penclawdd		v	Llanelli Wanderers

22 April 2023
Llanelli Wanderers		v	Crymych
Llangennech		v	Felinfoel
Pembroke		v	Gowerton
Penclawdd		v	Newcastle Emlyn
Whitland		v	Aberystwyth
Yr Hendy		v	Gorseinon

29 April 2023
Aberystwyth		v	Llanelli Wanderers
Crymych		v	Penclawdd
Felinfoel		v	Yr Hendy
Gorseinon		v	Whitland
Gowerton		v	Llangennech
Newcastle Emlyn		v	Pembroke