13 November 2021
Dinas Powys		v	St Peters
Porth Harlequins		v	Rumney
Rhydyfelin		v	Rhiwbina
St Josephs		v	Mountain Ash
Treorchy		v	Cambrian Welfare
Ynysybwl		v	Barry

27 November 2021
Barry		v	Treorchy
Cambrian Welfare		v	St Josephs
Mountain Ash		v	Rhydyfelin
Rhiwbina		v	Porth Harlequins
Rumney		v	Dinas Powys
St Peters		v	Ynysybwl

4 December 2021
Dinas Powys		v	Rhiwbina
Porth Harlequins		v	Mountain Ash
Rhydyfelin		v	Cambrian Welfare
St Josephs		v	Treorchy
St Peters		v	Barry
Ynysybwl		v	Rumney

11 December 2021
Barry		v	St Josephs
Cambrian Welfare		v	Porth Harlequins
Mountain Ash		v	Dinas Powys
Rhiwbina		v	Ynysybwl
Rumney		v	St Peters
Treorchy		v	Rhydyfelin

18 December 2021
Dinas Powys		v	Cambrian Welfare
Porth Harlequins		v	Treorchy
Rhydyfelin		v	St Josephs
Rumney		v	Barry
St Peters		v	Rhiwbina
Ynysybwl		v	Mountain Ash

8 January 2022
Barry		v	Rhydyfelin
Cambrian Welfare		v	Ynysybwl
Mountain Ash		v	St Peters
Rhiwbina		v	Rumney
St Josephs		v	Porth Harlequins
Treorchy		v	Dinas Powys

15 January 2022
Dinas Powys		v	St Josephs
Porth Harlequins		v	Rhydyfelin
Rhiwbina		v	Barry
Rumney		v	Mountain Ash
St Peters		v	Cambrian Welfare
Ynysybwl		v	Treorchy

29 January 2022
Barry		v	Porth Harlequins
Cambrian Welfare		v	Rumney
Mountain Ash		v	Rhiwbina
Rhydyfelin		v	Dinas Powys
St Josephs		v	Ynysybwl
Treorchy		v	St Peters

19 February 2022
Dinas Powys		v	Porth Harlequins
Mountain Ash		v	Barry
Rhiwbina		v	Cambrian Welfare
Rumney		v	Treorchy
St Peters		v	St Josephs
Ynysybwl		v	Rhydyfelin

5 March 2022
Cambrian Welfare		v	Mountain Ash
Dinas Powys		v	Barry
Porth Harlequins		v	Ynysybwl
Rhydyfelin		v	St Peters
St Josephs		v	Rumney
Treorchy		v	Rhiwbina

12 March 2022
Barry		v	Cambrian Welfare
Mountain Ash		v	Treorchy
Rhiwbina		v	St Josephs
Rumney		v	Rhydyfelin
St Peters		v	Porth Harlequins
Ynysybwl		v	Dinas Powys