13 November 2021
CR Cymry Caerdydd		v	Pontyclun
Llanharan		v	Pentyrch
Penarth		v	Old Illtydians
Penygraig		v	Fairwater
St Albans		v	Cardiff Quins
Tylorstown		v	Canton

27 November 2021
Canton		v	St Albans
Cardiff Quins		v	Penygraig
Fairwater		v	Penarth
Old Illtydians		v	Llanharan
Pentyrch		v	CR Cymry Caerdydd
Pontyclun		v	Tylorstown

4 December 2021
CR Cymry Caerdydd		v	Old Illtydians
Llanharan		v	Fairwater
Penarth		v	Cardiff Quins
Penygraig		v	St Albans
Pontyclun		v	Canton
Tylorstown		v	Pentyrch

11 December 2021
Canton		v	Penygraig
Cardiff Quins		v	Llanharan
Fairwater		v	CR Cymry Caerdydd
Old Illtydians		v	Tylorstown
Pentyrch		v	Pontyclun
St Albans		v	Penarth

18 December 2021
CR Cymry Caerdydd		v	Cardiff Quins
Llanharan		v	St Albans
Penarth		v	Penygraig
Pentyrch		v	Canton
Pontyclun		v	Old Illtydians
Tylorstown		v	Fairwater

8 January 2022
Canton		v	Penarth
Cardiff Quins		v	Tylorstown
Fairwater		v	Pontyclun
Old Illtydians		v	Pentyrch
Penygraig		v	Llanharan
St Albans		v	CR Cymry Caerdydd

15 January 2022
CR Cymry Caerdydd		v	Penygraig
Llanharan		v	Penarth
Old Illtydians		v	Canton
Pentyrch		v	Fairwater
Pontyclun		v	Cardiff Quins
Tylorstown		v	St Albans

29 January 2022
Canton		v	Llanharan
Cardiff Quins		v	Pentyrch
Fairwater		v	Old Illtydians
Penarth		v	CR Cymry Caerdydd
Penygraig		v	Tylorstown
St Albans		v	Pontyclun

19 February 2022
CR Cymry Caerdydd		v	Llanharan
Fairwater		v	Canton
Old Illtydians		v	Cardiff Quins
Pentyrch		v	St Albans
Pontyclun		v	Penygraig
Tylorstown		v	Penarth

5 March 2022
Cardiff Quins		v	Fairwater
CR Cymry Caerdydd		v	Canton
Llanharan		v	Tylorstown
Penarth		v	Pontyclun
Penygraig		v	Pentyrch
St Albans		v	Old Illtydians

12 March 2022
Canton		v	Cardiff Quins
Fairwater		v	St Albans
Old Illtydians		v	Penygraig
Pentyrch		v	Penarth
Pontyclun		v	Llanharan
Tylorstown		v	CR Cymry Caerdydd