13 November 2021
Bynea		v	Penygroes
Furnace United		v	Llangadog
Llandybie		v	Llandeilo
New Dock Stars		v	Cefneithin
Trimsaran		v	Betws
Tumble		v	Amman United

27 November 2021
Amman United		v	Trimsaran
Betws		v	New Dock Stars
Cefneithin		v	Llandybie
Llandeilo		v	Furnace United
Llangadog		v	Bynea
Penygroes		v	Tumble

4 December 2021
Bynea		v	Llandeilo
Furnace United		v	Cefneithin
Llandybie		v	Betws
New Dock Stars		v	Trimsaran
Penygroes		v	Amman United
Tumble		v	Llangadog

11 December 2021
Amman United		v	New Dock Stars
Betws		v	Furnace United
Cefneithin		v	Bynea
Llandeilo		v	Tumble
Llangadog		v	Penygroes
Trimsaran		v	Llandybie

18 December 2021
Bynea		v	Betws
Furnace United		v	Trimsaran
Llandybie		v	New Dock Stars
Llangadog		v	Amman United
Penygroes		v	Llandeilo
Tumble		v	Cefneithin

8 January 2022
Amman United		v	Llandybie
Betws		v	Tumble
Cefneithin		v	Penygroes
Llandeilo		v	Llangadog
New Dock Stars		v	Furnace United
Trimsaran		v	Bynea

15 January 2022
Bynea		v	New Dock Stars
Furnace United		v	Llandybie
Llandeilo		v	Amman United
Llangadog		v	Cefneithin
Penygroes		v	Betws
Tumble		v	Trimsaran

29 January 2022
Amman United		v	Furnace United
Betws		v	Llangadog
Cefneithin		v	Llandeilo
Llandybie		v	Bynea
New Dock Stars		v	Tumble
Trimsaran		v	Penygroes

19 February 2022
Bynea		v	Furnace United
Cefneithin		v	Amman United
Llandeilo		v	Betws
Llangadog		v	Trimsaran
Penygroes		v	New Dock Stars
Tumble		v	Llandybie

5 March 2022
Betws		v	Cefneithin
Bynea		v	Amman United
Furnace United		v	Tumble
Llandybie		v	Penygroes
New Dock Stars		v	Llangadog
Trimsaran		v	Llandeilo

12 March 2022
Amman United		v	Betws
Cefneithin		v	Trimsaran
Llandeilo		v	New Dock Stars
Llangadog		v	Llandybie
Penygroes		v	Furnace United
Tumble		v	Bynea