13 November 2021
Builth Wells		v	Resolven
Maesteg Celtic		v	Porthcawl
Pencoed		v	Morriston
Pyle		v	Heol y Cyw
Seven Sisters		v	Bridgend Sports
Ystradgynlais		v	Aberavon Quins

27 November 2021
Aberavon Quins		v	Seven Sisters
Bridgend Sports		v	Pyle
Heol y Cyw		v	Pencoed
Morriston		v	Maesteg Celtic
Porthcawl		v	Builth Wells
Resolven		v	Ystradgynlais

4 December 2021
Builth Wells		v	Morriston
Maesteg Celtic		v	Heol y Cyw
Pencoed		v	Bridgend Sports
Pyle		v	Seven Sisters
Resolven		v	Aberavon Quins
Ystradgynlais		v	Porthcawl

11 December 2021
Aberavon Quins		v	Pyle
Bridgend Sports		v	Maesteg Celtic
Heol y Cyw		v	Builth Wells
Morriston		v	Ystradgynlais
Porthcawl		v	Resolven
Seven Sisters		v	Pencoed

18 December 2021
Builth Wells		v	Bridgend Sports
Maesteg Celtic		v	Seven Sisters
Pencoed		v	Pyle
Porthcawl		v	Aberavon Quins
Resolven		v	Morriston
Ystradgynlais		v	Heol y Cyw

8 January 2022
Aberavon Quins		v	Pencoed
Bridgend Sports		v	Ystradgynlais
Heol y Cyw		v	Resolven
Morriston		v	Porthcawl
Pyle		v	Maesteg Celtic
Seven Sisters		v	Builth Wells

15 January 2022
Builth Wells		v	Pyle
Maesteg Celtic		v	Pencoed
Morriston		v	Aberavon Quins
Porthcawl		v	Heol y Cyw
Resolven		v	Bridgend Sports
Ystradgynlais		v	Seven Sisters

29 January 2022
Aberavon Quins		v	Maesteg Celtic
Bridgend Sports		v	Porthcawl
Heol y Cyw		v	Morriston
Pencoed		v	Builth Wells
Pyle		v	Ystradgynlais
Seven Sisters		v	Resolven

19 February 2022
Builth Wells		v	Maesteg Celtic
Heol y Cyw		v	Aberavon Quins
Morriston		v	Bridgend Sports
Porthcawl		v	Seven Sisters
Resolven		v	Pyle
Ystradgynlais		v	Pencoed

5 March 2022
Bridgend Sports		v	Heol y Cyw
Builth Wells		v	Aberavon Quins
Maesteg Celtic		v	Ystradgynlais
Pencoed		v	Resolven
Pyle		v	Porthcawl
Seven Sisters		v	Morriston

12 March 2022
Aberavon Quins		v	Bridgend Sports
Heol y Cyw		v	Seven Sisters
Morriston		v	Pyle
Porthcawl		v	Pencoed
Resolven		v	Maesteg Celtic
Ystradgynlais		v	Builth Wells